Normalize
Resolve gene symbols, aliases, receptor subunits, and order-independent complexes.
Evidence-first ligand–receptor analysis
Ligand–receptor evidence,
verified claim by claim.
Enter a human ligand–receptor pair. LRSniper maps receptor complexes, retrieves relevant literature, and checks every claim against PMIDs, quoted passages, species, and signaling direction.
Try an example
How it works
From a proposed pair to an auditable report.
LRSniper separates retrieval from verification so a plausible model answer never becomes evidence by itself.
Retrieve
Search local curated resources and external literature for each atomic claim.
Verify
Check PMID, verbatim passage, species, direction, and pair specificity.
Report
Return conclusions with evidence boundaries, failures, and machine-readable exports.
Example report
See the conclusion before reading every claim.
A compact executive summary shows what is verified, what is supported with limitations, and what remains context-dependent.
IL6→IL6R + IL6ST
Literature-supported interaction
- Pair identity
- Verified
- Receptor complex
- Verified
- Signaling direction
- Supported
- Sample activity
- Not established
Evidence standards
Uncertainty is a result, not an error.
Every status answers a different question. LRSniper keeps database support, direct literature evidence, conflicting findings, and unverified hypotheses distinct.
A resolvable publication contains pair-specific evidence that passes entity, species, and direction checks.
Relevant evidence was retrieved, but one or more strict verification conditions remain unmet.
A curated source supports the fact; this is not automatically sample-specific activity evidence.
The claim remains a search hypothesis and must not be treated as established biology.
Move faster without hiding the evidence boundary.
Literature triageHypothesis assessmentReceptor-complex validationCell–cell communication interpretation